Studies from Technical University of Dresden Describe New Findings in Antiarrhythmics

According to recent research from Dresden, Germany, “Arrhythmias are caused by the perturbation of physiological impulse formation, impaired conduction, or disturbed electrical recovery. Currently available antiarrhythmic drugs-perhaps with exception of amiodarone-are not sufficiently effective and are burdened by cardiac and extracardiac side effects that may offset their therapeutic benefits.”

“Detailed knowledge about electrical and structural remodelling may provide a better understanding of the mechanisms leading to generation and maintenance of arrhythmias especially in the setting of underlying heart disease and accompanying autonomic dysfunction. Thus, targets for new pharmacological interventions could include atrial-selective ion channels (e.g. atrial I-Na, I-Kur and I-K,I-ACh), pathology-selective ion channels (constitutively active I-K,I-ACh, TRP channels), ischemia-uncoupled gap junctions, proteins related to malfunctioning intracellular Ca2+ homeostasis (e.g. ”leaky” ryanodine receptors, overactive Na+,Ca2+ exchanger) or risk factors for arrhythmias (”upstream” therapies). In ventricular arrhythmias implantable cardioverter-defibrillator devices rather than antiarrhythmic drugs are the safest treatment option,” wrote U. Ravens and colleagues, Technical University of Dresden (see also Antiarrhythmics).

The researchers concluded: “The domain for new approaches to drug treatment is atrial fibrillation.”

Ravens and colleagues published their study in Naunyn – Schmiedebergs Archives of Pharmacology (Novel pharmacological approaches for antiarrhythmic therapy. Naunyn – Schmiedebergs Archives of Pharmacology, 2010;381(3):187-193).

For additional information, contact U. Ravens, Technical University of Dresden, Medical Faculty Carl Gustav Carus, Dept. of Pharmacology & Toxicology, Fetscherstr 74, D-01307 Dresden, Germany.

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Male Impotence Myths

Hippocrates, the father of medicine, said: “There are in fact two things, science and opinion; the former begets knowledge, the latter ignorance”. Those words still ring true today.

Many of the myths and legends about impotence, borne out of ignorance thousands of years ago, still influence our sexual culture. Primitive cultures believed that male virility was intricately interwoven with power, wealth and domination.

So it’s not surprising that beliefs still persist in a number of cultures that to lack virility, or worse still, to be impotent, is to lack the very essence of life. Manhood and the “ability to perform” are inextricably linked, so impotence is viewed as a “lack of manhood”.

Despite the fact that the twentieth century brought about radical changes in gender roles, on ethnic, economic, social and cultural levels, sexuality and impotence are still shrouded in mystery, secrecy and a good deal of confusion.

Myth 1 – “Real men” don’t experience impotence

ALL men over the age of 30 experience impotence as least once in their lifetime. It’s estimated that over 150 million men worldwide have impotence; in fact, reports suggest this figure could be as high as 300 million or more. Estimating the numbers is difficult because less than 2 men in 10 seek treatment for impotence problems.

Impotence (or erectile dysfunction) is defined as the inability to produce and maintain an erection sufficient for sexual intercourse. Impotence is not considered to include lack of libido, inability to ejaculate or achieve orgasm, a lack of strength or the loss of “manhood”.

Myth 2 – Impotence is “all in the mind

Less than 20 of impotence cases have a primary psychological cause. The majority of men with impotence have an underlying physical condition such as diabetes, heart disease, high blood pressure or prostate cancer. Stress, anxiety and loss of self-esteem are often secondary psychological factors that occur if the impotence remains undiagnosed and untreated.

Myth 3 – Impotence is a natural part of growing old

Although it’s evident that the chances of experiencing impotence increase with age, this is largely due to the increased risk of having an underlying physical condition such as diabetes, high blood pressure or heart disease. To compound this factor, a number of medications prescribed for these conditions can cause impotence.

Myth 4 – There is no “cure” for impotence

Although medical science hasn’t come up with a permanent “cure” for impotence, a number of very effective therapies are available. Oral medications such as Viagra have revolutionized the treatment of impotence, however impotence pills don’t work for everyone. Other safe and effective treatments include vacuum pumps, injections and penile implants.

Once the impotence is effectively treated, most men go on to lead active, satisfying sex lives.

Myth 5 – Impotence is a man’s problem

Both partners in a relationship can experience problems when impotence goes untreated. Often failure to communicate and denial of the problem lead to depression, anxiety, and lack of self-esteem for both partners. A tendency to avoid sexual contact can often leave the partner feeling unloved, unattractive and unwanted.

Myth 6 – Impotence is too embarrassing to discuss with anyone

A number of men find it very difficult to discuss any problems they may be experiencing, particularly impotence. Impotence can often be the symptom of an underlying medical condition and won’t simply “go away” if it remains untreated.

Once the condition is diagnosed, suitable treatment can begin immediately and the problem can usually be alleviated.

Myth 7 – Men should know all about sex

The general consensus of opinion is that men instinctively know how to have sex. But clinical studies confirm that impotence can result from lack of knowledge and ignorance about the “mechanics” of sex.

A common misconception is that sex is a simple and straightforward process for men. Not true. Many men find it difficult to discuss the subject, and asking questions would reveal their ignorance and lack of knowledge and possibly threaten their masculinity. Media images of the virile male in action only serve to further alienate those men who don’t understand “the basics”.

Talking to a specialist counselor or therapist will quickly clear up any misconceptions and help overcome problems due to lack of knowledge.

Myth 8 – Men always want sex

The myth that men are always “ready, willing and able” is simply not true. The commonly held misconception of the “dominant male” has been proven to damage the sexual, physical and psychological wellbeing of a number of men.

A recent Swedish study on sexuality and marriage carried out on 286 couples of varying ages found that men who perceived themselves to be the “dominant male” were more likely to experience temporary impotence if sex was requested by their partner, when they weren’t in the mood.

Healthy relationships should be about equal partnerships, good communication and respect for the feelings of both individuals. It’s not uncommon for one partner to want more frequent sexual activity, and sexual desires can fluctuate between partners and at various times. Discussing these issues reasonably and rationally so that each partner understands the needs of the other helps maintain a happy and healthy sexual relationship.

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Who Else Wants to Discover the Amazing Secret to Living Stress-Free!

ecover-stressfreeIn today’s fast-paced, rapidly-changing world, stress has quickly become a big part of our everyday lives.

The truth is these days it seems like stress is everywhere we are… whether we’re at work, at school, on the road and even at home – and being able to identify and cope with stress is fast becoming an essential life skill.

In fact, being unable to cope with stress has been shown to lead to a myriad of physical problems, including cancer, heart disease, fibromyalgia, migraines, gastrointestinal problems and arthritis, just to name a few.

So what can you do to simplify your life, reduce your harmful stress and protect your health?

Well, luckily for you the answers are now available in a new ebook entitled, “Living a Stress-Free Life.”

At Last! The Tips, Techniques & Secrets You Need to Know to Cope With & Eliminate Stress are Revealed!

The “Living a Stress-Free Life” ebook highlights time-tested techniques to identify stress and to reduce both our perception of it and its harmful effects.

Read this easy-to-follow guide and you will gain practical, effective skills to manage stress both at home and in the workplace.

You will learn how to simplify your busy, complicated life.

You will learn to identify stress-causing problems and decide what needs to be done to solve them quickly and easily using a step-by-step approach.

Your newfound stress management skills will lead to a calmer, simpler, more enriching life.

Here is even more of what you will learn by reading this amazing guide:

  • How to recognize stress – and why some people don’t realize that they are stressed or recognize the harmful effects it’s having on their life and health
  • Why not all stress is bad – and why some stress can even produce positive results in your life!
  • How to tell the difference between positive stress and negative stress – what you learn here may surprise you!
  • Common causes of negative stress – and how to overcome them!
  • Two questions you must ask yourself when dealing with stress – failure to do this could result in frustration and even greater stress down the line!
  • 26 effects of long-term stress – and how to recognize if you are currently developing any of these conditions!
  • 18 stress-causing problems that you may not currently consider stressors – and how to eliminate the cumulative stress they cause!
  • How to determine how much stress you are currently under – find out if you need help fast here!
  • How to determine what exactly is causing your stress – learn to do this and you’ll put yourself on the fast track to living a stress-free life!
  • The #1 stressor – and how to neutralize it fast!
  • 9 amazing tips for living a stress-free life – follow these tips and you’ll be feeling happier and healthier in no time!
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“Living a Stress-Free Life” contains all the tips, techniques and secrets you need to know to manage stress and begin living a much happier, more satisfying life.

This is the ebook that will allow you to finally break free from the tremendous stress you’ve been under – without having to take any risky medications with potentially harmful side effects. You’ll learn:

  • Why there’s so much stress today
  • Why not all stress is bad
  • The causes of negative stress
  • The health and psychological effects of stress – particularly long-term stress
  • How to tell how much stress you have in your life right now
  • How to determine what’s causing your stress
  • Tips for managing and overcoming your stress
  • And much more!

So What Are You Waiting For? Download Your Approval Copy of Living a Stress-Free Life” Today!

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